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KMID : 1138520100130030073
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Journal of Pharmacopuncture
2010 Volume.13 No. 3 p.73 ~ p.80
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Beneficial Effect of Paljeong-san Pharmacopuncture Treatment Combined with Peritoneal Injection on Glycerol-Induced Acute Renal Failure in Rabbits
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Lim Chi-Yeon
Kim Min-Ho
Lee Guem-San
Kim Hyung-Woo
Kim Bu-Yeo
Yun Yeo-Choong
Cho Su-In
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Abstract
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Purpose:The present study was carried out to determine if Paljeong-san extract (PJS) treatment exerts beneficial effect against the glycerol-induced acute renal failure in rabbits.
Methods:PJS was selected in the basis of invigorating kidney which can eliminate pathogens. Rabbits were treated with PJS pharmacopuncture on Shin-shu () point for 5 days right after the injection of 50% concentration of glycerol ( body weight).
Results and Conclusion: Glycerol injection caused an increase in serum creatinine and BUN level and urine glucose secretion, which were accompanied by a reduction in GFR. PJS Pharmacopuncture treatment combined with peritoneal injection showed beneficial effect on glycerol-induced acute renal failure by inhibition of serum creatinine increase and GFR decrease.
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KEYWORD
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Paljeong-san, Pharmacopuncture, Peritoneal Injection, Acute Renal Failure
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